Helicobacter pylori (HP):
Chronic gastritis is the most common cause. HP is a spiral-shaped bacterium that is taken orally by the mouth and forms an inflammation that we call gastritis. It resides under the mucus layer that covers the stomach mucosa and protects it from the stomach acid and other factors. HP sensitizes the stomach mucosa to acid and other aggressive factors by weakening some of the mucous layer of mucus that emanates from both the toxins it secretes and the immune response (the response of the body's immune system to the bacterial response) that the body makes against the bacteria. In developing countries, a chronic inflammation of life in the gastric mucosa is caused when it is not treated in childhood. It has been shown that about 80% of our population is infected with this bacterium, more in the coexisting population. Although HP infection is considered to be one of the leading factors in ulcer formation, it is suggested that not all people infected with this bacterium develop ulcers and that increasing numbers of HP negative ulcers have been detected in recent years, other factors besides HP in ulcer formation are also effective.
Today, it is seen as diseases that are considered to be caused by HP infection. HP World Health Organization (WHO) has been accepted as one of the first carcinogenic factors. The presence of bacteriocin can be demonstrated by tests such as endoscopic biopsy, urea-breath test, and antibody and antigen screening in blood and stool. Midede HP is cleansed from bacteria by using specific drug regimens in patients who have been identified. The efficacy of this treatment is around 80-85%.
Aspirin and antirheumatic drugs:
Such medicines increase the susceptibility of the mucosa to acid and other aggressive factors by causing the protective mechanisms in the gastric mucosa to weaken and form gastritis. The resulting gastritis can be passed without cessation without any symptoms, but it can also persist in chronic form and with complications such as ulcer / bleeding.
In some cases, the body's immune system (the immune system) may accidentally become activated against its own tissues and organs, creating substances and cells that damage these tissues and organs (autoimmunity and autoimmune diseases). Hypothyroidism (Hashimoto thyroiditis), Sjögren's syndrome, rheumatoid arthritis, lupus, type I diabetes are among these group diseases. Some cells in the gastric mucosa may also be targets of the immunization system, leading to the development of a disease that results from the loss of cells that secrete acid in the chronic gastritis and gastric mucosa. In these patients, anemia due to iron deficiency and vitamin B12 deficiency is seen in the body, which is called autoimmune gastritis and pernicious anemia. In these types of masts, the likelihood of developing stomach cancer increased in the later stages of life compared to normal people.
Alcohol and other chemical substances may cause damage to the gastric mucosa. When used at normal doses, alcohol that is not drunk in the fasting state is not expected to produce significant gastritis in the gastric mucosa.
The mucosal folds that cover the inner face of the scalp are called hypertrophic gastritis after rash and enlargement due to inflammation. One such type of gastritis is known as Menetrier's disease. As a result of excessive protein loss from the gastric mucosa, the protein level falls and edema occurs.