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ABOUT Nova IVF Fertility

• Benefits to Nova IVI Fertility

– Lab set up & Upgradation

– Training, monitoring & Review of Embryologists & Consultants

– Technology Transfer : Embryo grading system, Cryotop Vitrification, SIVIS & Reflection

– Quality control initiatives

– Quality Management

– Troubleshooting

Expertise

• Consultants – 2 in every centre.

• Embryologist – In-house, at least 2 in every centre

Andrologist – in every centre to handle male infertility

• Counsellors – Financial and physcological counsellor in every centre

• 2 embryologist from IVI, Spain - provides leadership to the clinical embryology teams & responsible for developing , monitoring & adherence to clinical protocols, training & evaluation of embryologists

• NIF provides opportunities to pursue academic interests like authoring papers & conduct research. Till now we have published 20+ original articles, 21 paper presentations & have written 10 articles for different textbooks

The Lab

• Separate Andrology & Embryology Lab

• Andrology lab:

– Equipped with Laminar Air flow, incubator & centrifuge machine

Strict semen analysis parameters – Pre-was & post wash analysis done

– One sample is processed & analysed at one time, avoids mixing

– Printed reports are given

• Embryology Lab:

– Located towards end of the center

– Standard & strict SOPs

– Class 10,000 modular laboratory

Advanced Technology

• Laboratories conform to European standards for equipment, operating protocols and clean room standard

• High value infrastructure

– Full proof air handling unit

– 3 types of incubators – Heracell, Benchtop & Time lapse incubator

High precision microscope

– Separate refrigerators for media storage

– Separate laminar air flows for media preparation & gamete screening

– Separate freezing and biopsy room

– Use of toxic free consumables,

– Separate cryocans for patients with infectious diseases

– Use of international quality media and consumables

• Droplet culture method for embryo growth

• Unique embryo grading system for NIF

• Surplus embryos: Frozen at blastocyst stage

Advanced Technology

• Expertise to perform :

– MACS

– DFI

– Laser assisted hatching –

– eSET

– Blastocyst culture

– Advanced genetic services:

Cryotop vitrification : Use of Kitazato kit- the best and most expensive in the world

• Stringent quality assurance and quality control

– Standard & strict SOPs

– Regular audits of doctors, embryologists and laboratory by IVI Spain

– Maintaining laboratory environment and monitoring on day to day basis

– Periodic validation of procedures/ equipment

– Annual Lab stop

IT Infrastructure

• Use of UBQ Medics & SIVIS for clinical application

• Medics: supports front end functions, billing etc

• SIVIS: proprietary software developed by IVI.

Stores patients information in the form of EMR from 1st OPD to ET and clinical pregnancy, if any.

• The information is stored real-time.

• This helps us in

– Evidence based practice since we have data of all the cases treated at NIF

– Helps us in performing retrospective studies

• Reflections software: Special software developed for embryologists for daily monitoring , which is monitored by IVI

Ethical Practices

Ethical By Choice Not By Chance!

• Clinical:

– Need based treatment plan for every patient

– Optimal stimulation protocols

– Informed consent at every stage

Self- cycles: self embryo transferred, No mixing of gametes

– OHSS Free clinics

– Double witnessing to rule out errors during transfer

– Max 2 embryo transferred per cycle

– Surplus embryos – grown till blastocyst stage & then stored – can be used for the same patient/can be used for research/can be thrown

• Commercial:

– Standard cost for every patient

– One price for all

Donation Program at NIF

• Use of gametes/ embryos intended for donation program

• OD cycles –

Extensive Screening for donors

– Dedicated donor

– No Sharing gametes of existing couples for donation

• ED Cycles –

– Extensive Screening for donors

– No Sharing of leftover embryos of existing couples for donation

Transparency in Treatment

• Real time data capturing and monitoring by SIVIS

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