Cholera is a disease characterized by acute and severe diarrhea due to intestinal infection caused by the bacterium named Vibrio cholerae.

In 1817 in Japan, in 1826 in Moscow, in 1831 in Berlin, Paris and London. Later outbreaks of London's immigration to Canada resulted in the deaths of many people, and then in 1892 they had an epidemic in Hamburg. Has no place in health tourism

It is only seen in humans. Vomiting and stools. In later years, it was important to be contaminated by water. This is evidenced by the more frequent occurrence in arid and desert-covered areas. It is usually seen in the summer months. Liquid and electrical loss of the patient can result in death.

Vibrio cholera produces a poison substance in the small intestine called "interioxin". This substance stimulates the enzyme called adenyl cyclase in the epithelial cells of the intestine. Cicloses lead to the proliferation of the monophosphate substance by the endosperm 3,5 so that the cells of the epithelium in the gut cause the body fluid to migrate and lead to fluid and electrical loss of the patient. Because the fluid and electrolyte passing through the gut is heavy and continuous diarrhea is thrown out of the body.

- Patient incubation time is 6-48 hours. At the end of this period a very watery and painless diarrhea occurs.
- After a few hours, she may have a cigarette liquor.
- Do not get vomited, your stomach starts.
-The result of vomiting and diarrhea is loss of salt and muscle starts to cramps.
-It comes in a bruise, a low-pitched voice particular to koler.
- Rough snow, falling eyes, wrinkled skin, such factors are identified.
-Tension drops.
-Heady pulse, starts feeling excessive thirst,
If this kind of symptom occurs, deaths of up to 60% will occur if not treated. If treated, this rate is reduced by 1%.

The treatment of cholera, which has a very high mortality risk and still leads to the deaths of thousands of people today, is actually quite simple. Treatment, also known as "oral rehydration therapy" (oral liquid therapy), can help your cholera patients get well soon. In this treatment, the patient is given a mixture of salt and glucose (isotonic) equivalent to normal fluid-electrolyte balance in the body to replace the loss of lost water and electrolytes (sodium, potassium, chlorine, bicarbonate) and provide energy to the patient who is not normally fed. The heavier illnesses (about 10-20% of total patients) that can not drink anything are given from the mixture vaginal. Antibiotics such as tetracycline and tetracycline are used for antibacterial treatment if the condition is very severe and urgent.

In order to prevent cholera, environmental conditions must be improved, cleanliness must be observed, only boiled water and cooked food should be eaten in areas where the disease is resident. The most important measure must be vaccinated.4-5 months immunity is gained and during this time the disease is protected.