The liver is the biggest visceral organ of our body that has more than 400 functions. Among its duties: synthesize important constituents such as primarily proteins, cholesterol, phospholipids and coagulation factors, excreting gall, cleaning so many chemical substance and drugs from body, regulating immune system and adjusting glucose level. So many acute and chronic diseases that affect liver may irrevocably affect these vital functions. It is compulsory that organ not making its duty will be replaced with a new liver through liver transplantation in the below mentioned cases that are not treated with the opportunities of the modern medicine. Today thanks to that liver anatomy is better understood and medical and surgical treatments are advanced, liver transplantation operations are done with 80-90% success ratio if the operation is done on

Main liver transplantation indications:

 Chronic liver disease (depending on the diseases such as hepatitis B and C, alcohol and biliary cirrhosis)

 Acute renal impairment (as a result of mushroom and drug poisonings)

 Liver tumor that is not able to be resected (hepatocellular carcinoma) and some liver benign tumors

 Metabolism disorders

 Massive liver injury

 Parasitic infectations

The organ that is necessary for the patients for whom liver transplantation decision have been taken is primarily to be found through the organs that are donated after the cerebral death. But in the cases at which donations after cerebral death does not fulfill the demand, alive donor transplantations from the relatives up to 4th degree may be done as in other transplantations. 70% of the livers of alive donors who are selected from completely healthy individuals may be taken for transplantation. Bleeding, venous and biliary duct problems and infections are among important complications that are seen after the surgery. As a result; the patients whose transplantation surgery timing is well organized may return their life as completely healthy individuals.